Due to their characteristic properties, biodegradable nature and non-toxicity, clay-biopolymer based composites have many applications in such advanced fields as drug release, antimicrobial activities, etc. Keywords: Clay-Polymer Composites, Nano Clay, Polysaccharide, Fibrous Clays, Halloysite-Chitosan, Montmorillonite-Chitosan, Kaolinite-Chitosan, Vermiculite Starch, Halloysite-Starch, Montmorillonite-Starch, Kaolinite-Starch, Cellulose. HNT-Cellulose, Kaolinite-Cellulose, Drug Release, Wound Healing, Tissue Engineering, Wastewater Treatment, Food Packaging, Flame Retardant Materials.