This book draws together anthropological studies of human-animal relations among Indigenous Peoples in three regions of the Americas: the Andes, Amazonia and the American Arctic. Despite contrasts between the ecologies of the different regions, it finds useful comparisons between the ways that lives of human and non-human animals are entwined in shared circumstances and sentient entanglements. While studies of all three regions have been influential in scholarship on human-animal relations, the regions are seldom brought together. This volume highlights the value of examining partial connections across the American continent between human and other-than-human lives.