Protein-lipid interactions as a field of study is now a mature area, and this volume of NewComprehensive Biochemistry has been published with two objectives in mind. Firstly, to look to thefuture, and try to envisage how the subject may develop in the near to medium future. Secondly, to presentcontrasting or complementary views on the same system. For example, the acetylcholine receptor is discussedfrom a predominantly structural aspect by Barrantes, and from the kinetic standpoint by Rankin, et al.The volume not only gives an update on specific aspects of the field, but also shows the way in whichthe phenomenon of protein-lipid interactions is now seemingly infiltrating many areas of biomembraneresearch, from recombinant DNA studies, protein insertion and assembly and reconstitution considerationsto structural studies of membrane proteins.