In this Handbook, experts across multiple disciplines, including psychology, criminology, education, law, and policy, focus on the interface between developmental science and law across crucial but also very different periods of development. Coverage includes topics such as prenatal and infant abuse; questioning of minor and elderly victims, witnesses, and suspects; treatment of at-risk individuals across multiple settings (e.g., criminal courts, immigration, custody, and adoption hearings); experiences in prison; reentry transitions after incarceration; and reproductive and end-of-life legal rights. Insightful and forward looking, the Handbook provides crucial foundational knowledge of the field and offers concrete suggestions for next steps and conclusions for practitioners and scientists who are working to push the field forward and use the knowledge for more informed decision-making.