This book explores the groundbreaking potential of CRISPR/Cas9 gene-editing technology in revolutionizing cancer treatment. This collection of chapters delves into the application of CRISPR/Cas9 across a variety of cancers, including lung, breast, brain, gastric, pancreatic, colorectal, liver, prostate, bladder, cervical, ovarian, and bone cancers. Each chapter provides an in-depth analysis of how CRISPR/Cas9 can target and modify cancerous cells at the genetic level, offering the potential for highly personalized and precise therapies. The book also addresses the growing challenge of cancer drug resistance, detailing how CRISPR/Cas9 is being employed to study, understand, and potentially reverse resistance mechanisms, offering new hope for patients who have exhausted conventional treatment options. Furthermore, the integration of nanoparticles for efficient delivery of the CRISPR/Cas9 system is highlighted, providing a promising avenue for overcoming delivery challenges in cancer therapy.
Contents:
- CRISPR/Cas9 in the Treatment of Lung Cancer
- CRISPR/Cas9 in the Treatment of Breast Cancer
- CRISPR/Cas9 in the Treatment of Glioblastoma
- CRISPR/Cas9 in the Treatment of Gastric Cancer
- CRISPR/Cas9 in the Treatment of Pancreatic Cancer
- CRISPR/Cas9 in the Treatment of Colorectal Cancer
- CRISPR/Cas9 in the Treatment of Hepatocellular Carcinoma
- CRISPR/Cas9 in the Treatment of Prostate Cancer
- CRISPR/Cas9 in the Treatment of Bladder Cancer
- CRISPR/Cas9 in the Treatment of HPV Cancers, Primarily Cervical Cancer
- CRISPR/Cas9 in the Treatment of Ovarian Cancer
- CRISPR/Cas9 in the Treatment of Bone Cancers
- CRISPR/Cas9 in the Study and Reversal of Cancer Drug Resistance
- Nanoparticles for the Delivery of CRISPR/Cas9 System in Cancer Therapy
Readership: Clinicians, researchers and graduate students working on cancer and/or gene editing technologies.