In this issue of Surgical Oncology Clinics, guest editor Dr. Jashodeep Datta brings his considerable expertise to the topic of Immunotherapy for Solid Tumors. Immunotherapy for solid tumors represents a transformative approach in the field of oncology, and has potential to offer durable responses and long-term remission, even in cancers that have been resistant to conventional therapies. This issue provides a contemporary appraisal of advances in immunotherapy technologies and applications for solid tumors, particularly as they related to the surgical management of these diseases. - Contains 14 relevant, practice-oriented topics including the innovative use of circulating tumor DNA as a biomarker to decipher immunotherapy responses; TCR-engineered T cell therapies for solid tumors; new innovations in CAR-T cell approaches; combining systemic and local/regional approaches to improve immunotherapy sensitivity; mRNA vaccines for cancer treatment; management of immunotherapy toxicities; and more- Provides in-depth clinical reviews on immunotherapy for solid tumors, offering actionable insights for clinical practice- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews