Human annihilation has never been so easy. Artificial intelligence-guided genetic-engineered nanotechnology and robotics (AI-GNR) are widely recognized as our most transformative technological revolution ever, yet we do not even have a common moral language to unite our pluralistic world to prevent an AI apocalypse should this revolution explode out of our control. This book is the first known comprehensive global bioethical analysis of AI and AI-GNR by defining the Thomistic-Aristotelian personalist foundation of the rights and duties-based social contract framework of the United Nations, and then applying it to AI. As such, it creates a compelling approach which will appeal to scientists, health professionals, policy makers, politicians, students, and anyone interested in our shared survival around shared solutions.