We are honored to present the papers of the II International Symposium on "Generation and Transfer of Knowledge for Digital Transformation" (SITIC 2023). The event, a global gathering, was held at the Starfish Cayo Santa María Hotel in the province of Villa Clara, Cuba, in conjunction with the IV International Scientific Convention of the Central University "Marta Abreu" of Las Villas. This unique location served as a melting pot of ideas and perspectives from across the world.