Scientific Essay from the year 2011 in the subject Medicine - Dentistry, , language: English, abstract: This study aims to evaluate the effect of the addition of chlorohexidine gluconate (CHX) (powder) on some physical, mechanical properties and antimicrobial effect. In this study two hundred and forty samples of heat cured acrylic resin (Major base-2) were prepared and divided into different groups. Control group (without the addition of CHX) and experimental groups (with the addition of CHX (powder) at (1%, 2%, 3%)) to evaluate transverse strength, tensile strength, surface hardness, dimensional accuracy, deflection, residual monomer in addition to antimicrobial effect for heat cured acrylic resin before and after the addition of CHX (powder). Results showed a statistically significant difference at (p0.05) between control and experimental groups. The addition of CHX (powder) into heat cured acrylic resin increases its flexibility in addition to it's antimicrobial effect. Group of 1% CHX has the highest value of transverse strength, tensile strength, surface hardness and dimensional accuracy after control group. In addition to its antimicrobial effect, CHX increases the flexibility of heat cured acrylic resin. As the concentration of added CHX increased, the flexibility of heat cured acrylic resin specimens will be increased.