This book focuses on the future direction of dental research in every discipline. In this context, dental research must be deliverable to society, not just to churn out scientific publications but to truly change protocols applied in the clinic. Most of the topics covered in this book discuss the current trends and future advances in clinical dentistry as well as dental research. The book covers advances in research, future perspectives and challenges faced in different disciplines of dentistry. Various chapters discuss the recent advances in materials, methods and diagnostics, as well as their future implications. The contents review the applications of big data, artificial intelligence and machine learning in various branches of dentistry like orthodontics, prosthodontics, periodontics, pediatric dentistry, endodontics and oral and maxillofacial surgery. With the world moving into the digital age and advancing technology, we have collated the latest developments in the field of dental research.