The renowned Wellcome Library houses a number of - often literally - unique and rare Sanskrit and Indian vernacular manuscripts, collected by Sir Henry Wellcome himself in the early twentieth century.The present catalogue by David Pingree is the first guide to the important Wellcome collection of manuscripts containing texts on jyotihsastra, which includes astronomy, mathematics, divination and astrology, and covering well over a thousand manuscripts.Descriptions feature information, e.g., on scribes, owners and their families, thus providing much that will prove useful for those studying not only Sanskrit scientific manuscripts themselves, but also their creation, distribution and preservation. A true treasure-trove.