This issue of Radiologic Clinics of North America focuses on Breast Imaging and is edited by Dr. Phoebe E. Freer. Articles will include: Management of High-risk Lesions in Breast Cancer; Contrast Mammography and Tomosynthesis; Breast Radiology Advocacy: Responding to the Call-to-Action; Artificial Intelligence and Breast Imaging; Is It the Era for Personalized Breast Cancer Screening?; Understanding the Mammography Audit; MRI Screening of Breast Cancer; Abbreviated MRI for Breast Cancer; Overdiagnosis and Risks of Breast Cancer Screening; MRI Audit of Screening and Diagnostic Breast Imaging; Supplemental Screening for Breast Cancer in Patients at Intermediate and High Risk; and more!